Tylenol Linked To Autism & Used In Up To 90% Of Children

A narrative review of the evidence
The goal of Parker’s latest study was to pull together the many pieces of evidence in order to better understand the big picture.
The study is a narrative review that presents the 17 lines of evidence suggesting acetaminophen is associated with ASD and examines the alternative explanations.
Highlights from the review include:
• Acetaminophen use in pregnancy is neurotoxic to babies, with long-term effects that include lower IQ, increased ASD and increased ADHD. The authors conclude if babies can be harmed by acetaminophen in utero, it’s unreasonable to think they couldn’t also be harmed by the drug after birth.
• Studies on rats and mice showed acetaminophen causes long-term brain damage, and this early exposure to the drug was at doses that are similar to or even less than doses received by human babies and children. An alternative explanation is that rat and mouse pups are more sensitive to acetaminophen than human babies. However, the authors point out that lab animals are often less sensitive to toxins, such as the heavy metal lead and the insecticide DDT.
• The incidence of ASD began to increase in the early 1980s, coinciding with the discovery aspirin was associated with Reye’s syndrome and the resulting switch from using aspirin in children to using acetaminophen.
The authors argue this was not a coincidence.
• The incidence of ASD steadily increased in the U.S., after the U.S. Food and Drug Administration (FDA) eased restrictions on direct-to-consumer advertising in 1997. That, and other factors, may have increased the use of pharmaceutical products.
• The circumcision of baby boys is associated with a dramatic increase (50%) in the risk for early-onset ASD. Acetaminophen is frequently used to relieve pain caused by circumcision.
• The combination of the measles-mumps-rubella (MMR) vaccine with the use of acetaminophen is associated with higher risk of ASD than MMR vaccination alone. “Many parents believe that their children’s ASD was induced by a vaccine based on their own observations or the observations of trusted social networks.”
However, the authors argue the vaccination caused oxidative stress. The subsequent administration of acetaminophen — not the vaccine — then triggered the ASD.
• People with cystic fibrosis, who are unusually efficient at metabolizing acetaminophen, have a low incidence of ASD.
• In South Korea, where acetaminophen-containing products were repeatedly found to contain amounts of the drug exceeding the package label, researchers found an unexpectedly high prevalence of ASD.
What can parents do instead? Alternatives to acetaminophen

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