To me there definitely is. The Cryo hops pint is draft beer (which I think has a texture and authenticity on its own over a can) and more processed hops for a pronounced bitterness. The side launch is a lot less of all of that and just a good beer. The Major Tom is like if you took both of those beers, blasted it with sweetness and dumped a shot of vodka in it for more of a decadent sipping beer you have to get used to.
To someone who like plain lawnmower beer and lagers, they would all taste like a mouth full of sugared pine cones. ;)