im still looking into this Niacin toxicity, it appears to do something called Methylation, that Thiamine seems to actually undo.
found a few papers collaborating this, in a round about way, its the sulfur in Thiamine that helps unzip that kind of bond.
it appears Nitrogen & Sulfur need to be at the very exact balance, which Thiamine naturally does, even in its synthetic form.
i have links & notes about it, but its difficult to present everything all together, so its still not for certain.
wife gave me her cold, just started hitting me today, and B1 & the correct minerals do not prevent a cold, so went back to my trusty old vinegar minerals, holding it in my mouth, letting everything soak in, and can feel a difference, like last time i almost got sick, it stopped it completely & immediately, so about to find out if it still works.
my vinegar minerals is the kitchen sink, full bottle of vinegar, tables spoons of all the minerals, honey, vitamins, live probiotics, Niacin ect.. everything i got went in, makes it kinda like fulvic acid.
i put everything all in, as a last ditch effort, and kind of forgot about everything last few months, atcthe beginning it was a bit too hot, but after sitting for months, now its got a new feeling about it.
this is why i wanted to put it all together & cook it down like a bone broth, make the elements break down faster, but just letting it sit for awhile does the same thing.
its like an antihistamine.
and fulvic humuic aciid, its so complex, the microbes dont know what to do, and the body is good at using it.