An article published in Consumer Reports in 2006 recommends avoiding the fat-burning supplements 5-hydroxytryptophan, or 5-HTP, and citrus aurantium, also called bitter orange, as these both have potentially serious side effects. Bitter orange can cause increased heart rate, anxiety and chest pain, and 5-HTP can cause inflammation and pain in the joints and muscles and severe gastrointestinal issues. Another article, published in the Canadian Journal of Gastroenterology in 2011, notes that an herbal fat-burning supplement containing usnic acid, guggul tree and green tea extracts was linked to a case of liver failure. copied
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