I Read Way Too Many Studies About Vitamin D So You Don't Have To

[chiren]

Vitamin D Supplementation: What the Science Actually Says

So here's the thing about vitamin D supplements. If you're living anywhere north of, say, Los Angeles—we're talking Montreal, Boston, New York, pretty much all of Canada and Northern Europe—you've definitely been told to pop some vitamin D pills during winter. But is this actually backed by science, or is it just clever marketing from the supplement industry?

I went down a bit of a research rabbit hole on this one, and honestly? The answer is way more interesting than a simple "yes" or "no." Turns out, whether vitamin D supplements actually help you depends a lot on where you're starting from.

The Core Truth: It Depends on Your Vitamin D Levels

Okay, so here's what the big research studies actually found: if you already have good vitamin D levels, taking more won't really do much for you. A bunch of large randomized controlled trials from 2017-2020 looked at people who were already vitamin D-replete (fancy term for "you have enough"), and found that giving them supplements didn't help with cancer, heart disease, diabetes, bone density, or falls[1].

But—and this is a big but—if you're actually deficient? That's a completely different story. When researchers went back and looked specifically at people who started out with low vitamin D, they found that supplementing helped slow down age-related bone loss and the progression to type 2 diabetes, plus it improved lung function[1]. There's also solid evidence that vitamin D supplements can modestly reduce cancer mortality, especially when you take them daily instead of in those huge once-a-week or once-a-month megadoses[2][3].

So the real question isn't "should I take vitamin D?" It's "do I actually need it?"

The Northern Latitude Problem

And here's where living in the north becomes a real issue. If you're spending your winters in a northern city, chances are pretty high that you're deficient—whether you know it or not.

The science on this is actually really clear: if you live north of 35 degrees latitude (that's roughly the line from LA across to Atlanta), you literally cannot make enough vitamin D from the sun during winter. The sun's rays just aren't strong enough to trigger vitamin D production in your skin[4][5]. So all those sunny winter days? Yeah, they're nice for your mood, but they're doing basically nothing for your vitamin D levels.

The numbers are kind of wild. In Buffalo during winter, almost 50% of people have insufficient vitamin D and a quarter are straight-up deficient[5]. Boston researchers studying schoolchildren found that over 90% were vitamin D deficient in winter, with 40% being seriously deficient[6]. These aren't small numbers.

Now, your body does store up vitamin D from summer sun exposure, which helps keep you from hitting rock bottom in winter. But experts say don't count on that—keep supplementing year-round[4].

Who's Most at Risk?

Some folks have it even worse when it comes to vitamin D:

• People with darker skin: Melanin basically acts like built-in sunscreen, so you need way more sun exposure to make the same amount of vitamin D as someone with pale skin[4]
• Older adults: Your skin gets worse at making vitamin D as you age[5]
• Pregnant and nursing folks: You need extra for your baby's bone development[7]
• People with obesity: Tends to make it harder for your body to respond to vitamin D supplements[6]
• The sunscreen devotees and sun-avoiders: If you're rarely outside or always covered up, you're probably low

For high-risk populations in northern areas, health authorities actually bumped up recommendations from 400 to 800 IU per day during winter[7].

How Much Should You Take?

So this is where it gets a bit annoying—different health organizations give different recommendations:

• US Institute of Medicine: 600-800 IU per day for adults[8]
• Endocrine Society: 1,500-2,000 IU per day for optimal levels[8]
• For northern winters specifically: 1,000-2,000 IU per day of vitamin D3[5]
• Don't go above: 4,000 IU per day (that's the safety ceiling)[8]

Here's something interesting: that Boston study on kids found that getting vitamin D-deficient children up to healthy levels took more than three times the standard recommended dose[6]. So if you're starting from a really low place, the usual recommendations might not cut it.

Oh, and make sure you're getting D3, not D2—research shows D3 works better, especially if you're taking it weekly or in bigger doses[9].

Beyond Bone Health

Okay, so we all know vitamin D is important for bones (preventing rickets in kids, keeping bones strong in adults). But what about all those other health claims you see floating around? Here's what the research actually shows:

Respiratory infections: Some studies found that vitamin D might help prevent colds and flu, especially if you start out with low levels[10]. Not a guarantee, but potentially helpful.

Heart health: A 2024 analysis found that vitamin D supplementation improved blood pressure, cholesterol, and blood sugar—but mostly in people who weren't Western, had really low vitamin D to start with, weren't obese, and were over 50[11]. So, pretty specific conditions.

Muscle strength: Studies on athletes showed some benefits for leg strength, but nothing dramatic across the board[12].

Critical illness: This one's actually pretty interesting—for ICU patients on ventilators, vitamin D supplementation significantly helped with survival rates and recovery time[13]. But obviously, this is a very specific situation.

The pattern here? Vitamin D seems to help when you're deficient or in specific health situations, but it's not some magic cure-all.

The Testing Question

So should you actually get your vitamin D levels tested? A 25(OH)D blood test can tell you exactly where you stand. The general consensus on what the numbers mean:

• Below 20 ng/mL: Deficient (not good)
• 20-30 ng/mL: Insufficient (meh)
• 30-50 ng/mL: Adequate (you're fine)
• 50-60 ng/mL: Optimal (some experts think this is ideal)

Getting tested makes the most sense if you're in one of those high-risk groups, or if you just want to know for sure before you start supplementing. It takes the guesswork out of it.

The Bottom Line for Northern Dwellers

Alright, here's my take after reading through all this research: if you live up north and spend your winters indoors like a normal human being, yeah, you should probably be taking vitamin D supplements—and not just in winter, but year-round.

This isn't about chasing some miracle health transformation. It's just about preventing deficiency and keeping your body functioning the way it should. The research is pretty clear that supplements won't magically make you healthier if you're already at good levels, but letting yourself become deficient is legitimately bad for your bones and potentially other stuff too.

In northern latitudes during winter, getting enough vitamin D from the sun just isn't happening. Like, physically impossible. So supplementation isn't optional if you want to maintain healthy levels—it's literally the only way.

For most adults living in the north, taking 1,000-2,000 IU of vitamin D3 daily during winter (or all year) is both reasonable and safe. And here's the good news: vitamin D3 supplements are usually pretty cheap. You can buy them in bulk bottles that'll last you months for like 10 bucks, so cost really isn't a barrier here.

But obviously, chat with your doctor about it, especially if you've got health conditions or take medications that might interact with vitamin D.

Stay healthy out there, and don't let the winter darkness get you down (literally)!

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References

[1] Bouillon, R., et al. (2021). The health effects of vitamin D supplementation: evidence from human studies. Nature Reviews Endocrinology. https://www.nature.com/articles/s41574-021-00593-z

[2] BMJ. (2020). Association between vitamin D supplementation and mortality: systematic review and meta-analysis. BMJ, 370:m2329. https://pubmed.ncbi.nlm.nih.gov/32963015/

[3] Zhang, Y., et al. (2019). Vitamin D supplementation and total cancer incidence and mortality: a meta-analysis of randomized controlled trials. Annals of Oncology. https://www.annalsofoncology.org/article/S0923-7534(19)31159-7/fulltext

[4] Consensus AI. (2025). Can People North of 35deg Latitude Get Enough Vitamin D via the Sun in Winter? https://consensus.app/home/blog/can-people-north-of-35deg-latitude-get-enough-vitamin-d-via-the-sun-in-winter/

[5] University at Buffalo. (2015). People who live in northern cities during winter at risk for vitamin D deficiency. https://lesliebeck.com/articles/2015/02/18/people-who-live-in-northern-cities-during-winter-at-risk-for-vitamin-d-deficiency

[6] Sacheck, J.M., et al. (2017). Impact of Three Doses of Vitamin D3 on Serum 25(OH)D Deficiency and Insufficiency in At-Risk Schoolchildren. The Journal of Clinical Endocrinology & Metabolism. https://medicalxpress.com/news/2017-10-kids-northern-latitudes-dont-vitamin.html

[7] Canadian Paediatric Society. (2007). Vitamin D supplementation in northern Native communities. Paediatrics & Child Health. https://pmc.ncbi.nlm.nih.gov/articles/PMC2795675/

[8] The Conversation. (2025). Why you need more Vitamin D in the winter. https://theconversation.com/why-you-need-more-vitamin-d-in-the-winter-128898

[9] VitaminDWiki. Meta-analysis of Vitamin D. https://vitamindwiki.com/Meta-analysis+of+Vitamin+D

[10] Martineau, A.R., et al. (2017). Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis. BMJ, 356:i6583.

[11] Chu, X., et al. (2024). Modifiers of the Effects of Vitamin D Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Journal of Sport and Health Science. https://www.sciencedirect.com/science/article/pii/S2095809924003990

[12] Han, Q., et al. (2024). Effects of vitamin D3 supplementation on strength of lower and upper extremities in athletes: an updated systematic review and meta-analysis. Frontiers in Nutrition. https://pubmed.ncbi.nlm.nih.gov/38860160/

[13] Zheng, W.H., et al. (2025). Vitamin D supplementation in critically ill patients: a meta-analysis. Frontiers in Nutrition. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1505616/full

Comments

[irivers]

It would be helpful if local news reported the UVB index during the winter.

I am of the opinion that the sun is the best source for vitamin d as naturally metabolized vitamin D is likely to provide the best balance of the different forms of the vitamin.

BTW have you studied the connection between free fructose found in HFCS and invert sugar and vitamin D?

!WINE

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[chiren]

Great point about the UVB index—that would be super useful info to have during winter!

I hear you on sun being the best source. The problem for those of us up north is that above ~35° latitude, the sun's angle in winter literally can't produce vitamin D, even on sunny days. The UVB rays just don't penetrate at that angle. So it's basically sun in summer, supplements in winter, or risk deficiency.

Haven't looked into the fructose/vitamin D connection—that's interesting though! Got any studies on that? Sounds like a potential rabbit hole.

Thanks for the comment!

[irivers]

I've seen popular science articles about the interaction between vitamin d and the free fructose in HFCS.

I haven't drilled down to scientific articles.

The same problem happens with invert sugar and agave nectar.

My understanding is that sucrose is a combination of fructose and glucose.

To make invert sugar, one processes the sucrose to separate the glucose from the fructose. this makes this sweeter. they do the same thing with agave nectar.

The free fructose acts like a radical which damages vitamin d.

I believe that the studies in this area are relatively new. If it is true then hfcs, invert sugar and other processed sugars are weeking our immune systems.

It might make an interesting article.

!BEER

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