The issue I have with pesticides is not a concern for my health, they are safe for humans if used in proper quantities and food is washed and prepared properly. I ise less because I know my neighbors use it too.
Modern pesticides are applied like vaccines, heard immunity. The idea isn't to make your crop toxic, it is to get the pests down to a level where organic and non chemical solutions can handle things.
The concern is for the ecosystem. It may harm other animals like frogs and birds. Also, even if it doesn't kill them or adversely affect them, it definitely kills the insects, their food supply.