Well, I for one haven't been able to ride a bicycle for years due to my health issues. I would love to buy an e-bike, but I can't afford one. So I'm stuck walking everywhere, which is getting harder now too, and I can't go as far as I used to, so I almost never leave my apartment. Public transport here sucks, so it still requires lots of walking and hours of time that exhausts me too.
That being said, I wouldn't be dressing in some spandex sausage skin (that term cracked me up, by the way) to ride one, I'd be wearing my normal clothes to ride to the grocery store or whatever. I didn't wear spandex when I was able to ride a regular bike, since for me it was my transportation and not a race or leisure exercise (and even then, I struggled with it, no matter how much I did it. I used to ride it 4 miles one way to and from my work nearly every day and it never got any easier. I've always had some health issues that were just ignored). I can't imagine going fast enough on a bicycle, e- or otherwise, to run over a mouse. Do e-bikes even go that fast that you couldn't stop in time? I thought they had speed limits, though I suppose if you were rolling downhill at full speed and pedaling at the same time, maybe.
Sorry bout your health issues dude. And to answer your question, yes you can run a mouse over with a bike. It is not necessarily the speed but the impact that killed the poor lil thing.
I just blame the cyclists because they annoy me lol.😄