Part 7/14:
Sickness behavior also involves neuroinflammation, where cytokines in the blood signal the brain to alter cognition and perception—often causing symptoms like photophobia and mental fog. Sleep is promoted, particularly during early stages of infection, aiding in immune system function. Huberman highlights that inflammatory cytokines such as IL-6, IL-1, and TNF-alpha can influence brain function, affecting cognition and mood during illness.
Activating the Nervous System to Boost Immunity
One of the central themes is the bidirectional relationship between the nervous system and immune defenses. Notably, activation of certain neural pathways can enhance immune responses or reduce inflammation. Huberman discusses strategies such as: