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During the initial 12 hours of fasting, glycogen stores from muscles and liver are depleted. After approximately 12 hours, the body begins mobilizing visceral fat to produce energy, releasing fatty acids that the liver converts into ketones—an alternative, cleaner fuel source. This shift not only promotes fat loss but also reduces inflammation, especially from the dangerous visceral and ectopic fat deposits around organs and the heart.
The Role of Visceral and Ectopic Fat in Inflammation and Disease
Visceral fat isn't merely a passive storage depot; it's metabolically active and highly inflammatory. It's laden with inflammatory cytokines that elevate systemic inflammation, contributing to insulin resistance and cardiovascular disease.