Part 6/9:
Initial human trials explored the effects of NAD⁺ augmentation through NR and NMN supplementation. One study involving middle-aged and older adults noted increased NAD⁺ levels with minimal side effects and suggested potential therapeutic effects for conditions like heart disease. Another study focused on postmenopausal women with pre-diabetes, revealing improvements in insulin sensitivity among those taking NMN.
Further research through a comprehensive analysis of multiple studies indicated that increasing NAD⁺ may aid in managing cholesterol levels, a vital component of overall health, particularly as we age. Additionally, some evidence pointed to reducing chemical signals associated with chronic inflammation, which is linked to various age-related diseases.