Part 4/6:
- Administering drugs to older mice to block and eliminate IL-11 activity.
Both approaches yielded notable lifespan extensions and health benefits, demonstrating the feasibility of targeting IL-11 as a longevity intervention.
Translating Research to Humans
Interestingly, a drug designed to inhibit IL-11, specifically for treating lung fibrosis, has already been tested in humans. Although its current use relates to respiratory health, its mechanism—blocking IL-11—mirrors the strategies used in mouse studies to promote healthier aging.