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In response to the mounting speculation, Schumer took to Instagram to address the rumors directly. She thanked followers for their concern and acknowledged that her appearance was “puffier than normal.” She clarified that she was dealing with health issues, specifically mentioning endometriosis, although health experts clarified that endometriosis is not classified as an autoimmune disease but an inflammatory condition. Schumer explained her current state as influenced by hormonal and medical factors, emphasizing that her physical presentation should not define her worth.