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MSM works primarily by increasing cell permeability, allowing toxins stored in tissues, the gut, or even the brain, to be released and expelled. This detoxing process is beneficial but can create temporary discomfort, especially if detox pathways are congested or overwhelmed.
Tolerance to MSM varies among individuals. While some experience immediate benefits, others may encounter detox reactions—signaling that the body is processing and removing stored toxins. These reactions are not indicative of MSM being unsafe but rather a sign that your body needs support.