The Monday vote in Philadelphia marks the first successful union campaign at a Whole Foods since it was acquired in 2017.
Employees at a Whole Foods store in Madison, Wisconsin, voted to join the UFCW in 2002, but employees at that store dissolved the union in 2003.
The labor victory comes as Amazon has faced a groundswell of union activity among its warehouse and delivery workforce in recent years. Employees have sought to unionize to obtain higher wages and improvements to working conditions.