“We show that by changing their diet, the stem cells can rejuvenate and turn into ‘super stem cells’. It forces them to metabolize their energy in a different way than they normally would, and that process essentially reprograms the stem cells,” says first author Robert Bone.
“What is really striking is that they’re not just better at differentiating, but they stay fit and keep healthy much better over time compared to stem cells in standard culture conditions. And it is done with a relatively simple method,” adds corresponding author Joshua Brickman.