I am using the first case you've put. (2 fans, heat sink case.)
I run Homebridge, Deconz, Adguard on a rpi4b (4gb), it was working round 38-40 degrees. But the fan noise was a lot. Since it's 5V gpio, I cannot manage it via software easily. (like, if it become too hot, open fans, etc.)
Disabled the fans for now, and rpi works around 49-50 degrees. Which is not optimal but good enough :)
And this is a cool automation that if rpi cpu temp. passes 52 degrees, my workspace lights become red. :)
Nice, I was checking that out after your post. I'm also going to give AdGuard a try and see how it performs against PiHole.
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