Missile Command was originally released as an arcade game by Atari in 1980 and was one of the games that made arcades and Atari popular. The premise is pretty simple. Nuclear missiles are raining down on your cities and it is your job to shoot them down before they strike. I guess you could say it was the perfect Cold War era game.
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I've played some of the Windows clones of that game.
Missile Command (and a bunch of other old Atari games) can be played in your browser here: http://my.ign.com/atari/missile-command
Looks like the arcade version. Probably emulated.