After watching Mayweather's fight against Pacquiao, I think Mayweather will try play his defensive game again, winning on points. McGregor will come with the south paw hooks to get around Mayweathers tight defense, landing body shots or left uppercuts. I truly believe McGregor has got this, but like you said, he can't take hits, so it will come down to what game plan the money team uses.
Edit: McGregor probably wont be able to endure past the fifth round, so he has to go for a quick knockout.