Hi:
A very thorough blog.
I was interested in the second reference you cited
Kenarova, B, H Neychev, C Hadjiivanova, and V D Petkov. 1990
I'm really careful about "immune-modulating" substances, because I have autoimmune issues. I looked up a few articles to see if ginseng was associated with flares for people who have these issues. It seems there is a suggestion by some sources that ginseng can be associated with flares because of its immune stimulative effect. This is probably not relevant for most people.
Here's some information I found in a quick Google search:
https://jamanetwork.com/journals/jamadermatology/fullarticle/480602
https://cmjournal.biomedcentral.com/articles/10.1186/1749-8546-6-21
The next one refers to Asian ginseng, while you refer specifically to American ginseng--don't know if there is a carry-over in effect.
http://pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000249
Johns Hopkins publishes a list of quite common foods that may cause lupus flares (this is not a rare autoimmune disease). Ginseng is not on the list, but some other surprising items that are supposed to be "good" are on it: garlic, alfalfa sprouts, melatonin, and echinacea. Here's the link.
https://www.hopkinslupus.org/lupus-info/lifestyle-additional-information/avoid/
Hope you don't mind my adding this to your post--it's just that people with hyperactive immune systems react in odd ways to "normal" substances. Your article on ginseng reminded me of that fact.