Thanks for the comment!
I am no expert, but certainly it seems that the correlation between A-beta and symptoms is weak at best and so there must be a lot more going on.
From what I read a fair amount of research is now focused on combination therapies targeting a number of different pathways - which makes sense in terms of moving things forward, but unfortunately I imagine only in small incremental steps.
But for sure, something is better than nothing and if you learn something from those steps then eventually the right path will show itself...
Cheers
The correlation between A-beta and symptoms is fantastic, it's why so many have been targeting it. Unfortunately those drugs modulating the plaque formation never seem to have the effecacy that we want, nor do they repeat the results we observe from them in animal models. It's odd. It's amazing just how much money has been poured into Alzheimer's (tens to hundreds of billions at this point) for such little progress to have been made.
Yeah, sorry, I am confusing myself now trying to do too many things at once - could be early onset Alzheimer's...
Sounds like you know your stuff!! More than I do at least 😁
Thanks for the comments!
Cheers
And thank you for the great post! Looking forward to what you have to bring to the table in the future :)
Thanks, will look for something healthcare next week. I try to do min one healthcare and one beer post per week. Beer today naturally...
Cheers