As one who uses labeled proteins (albeit they are mostly "just" antibodies), but never really spent more than a brief thought on how they are labeled, I have to say this was interesting to read.
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As one who uses labeled proteins (albeit they are mostly "just" antibodies), but never really spent more than a brief thought on how they are labeled, I have to say this was interesting to read.
There is actually quite a bit of neat chemistry going on even in standard protein labeling techniques! Actually there is quite a bit of neat chemistry going on everywhere, we just don't think about it much of the rime.
Thanks for checking the post out Sco. I went much more technical in my explanation this time, though I still summarized a lot and omitted big chunks of info from the paper for the sake of brevity and telling a story.