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There was one study that mentioned a weakened grip from it. That could affect your ability to play some instruments. Then again, the study was just a survey of elderly people in a retirement home. They separated them into groups of people who remember being knuckle poppers and those who weren't. I guess the knuckle poppers had a weaker grip; but, I'm not sure that shows an actual correlation between the two things.

I see... It gives us an Idea at least. We need to wait for further development