Part 3/15:
Dr. Kahn points out that many epidemiological findings are based on questionnaires reliant on memory, which is unreliable. Early studies from the 1950s and 60s suggested a connection between saturated fats and cholesterol increases, leading to guidelines favoring low saturated fat intake. However, recent meta-analyses of tens of thousands of randomized controlled trials (RCTs)—the gold standard—fail to confirm that saturated fat intake directly increases heart disease risk or total mortality.