Part 10/15:
Dr. Kahn explains that the relationship between saturated fat and heart disease is more robust, with over two dozen meta-analyses of randomized trials and observational data affirming that reducing saturated fat lowers LDL cholesterol and, correspondingly, most experts agree it reduces cardiovascular risk.
Chris argues that many of the epidemiological studies linking red meat to cancer or heart disease suffer from biases, questionable data collection methods, and overinterpretation of small relative risks. He emphasizes prioritizing direct clinical outcomes—mortality, heart attacks—over mechanistic markers, which may be misleading if not confirmed in real-world settings.