Hi! Thanks again for this very instructive blog. I especially enjoy the cholesterol part, which I know will affect me at some point (at this is in my genes, somewhat).
I have so far a single question.
Adipose tissues are simply loose fats cells and they play role in fat storage. One of the remarkable thing about this cells is that, the moment they reach their storage capacity threshold, they replicate and produce more adipocytes that will enable the store more fats cells.
After reading the above paragraph, I was wondering whether there was a way to act directly on the adipose tissues themselves (instead that on cholesterol) to be able to lose weight without doing anything special? Apologies in advance for the stupid and naive question. Maybe this is something I didn’t get right. Thanks in advance for clarifications.
Have a nice end of the week!
Haha, sir, your questions are always on point. Never stupid ones as they even sometimes unveil areas I might have forgotten to elaborate.
On the question, let me make it clearer;
Adipocytes are scattered around the body at some strategic regions and not that they only store fat. They also play good role by assisting in body insulation against Cold or heat. They even also produce Very important hormones the body needs e.g angiotensin that is involved in blood pressure control.
It is logically right to think that by stopping their replicative ability, weight can be reduced. But this will only be possible through molecular approach through gene alteration (not so easy but not impossible).
But since, their replication only occurs when they have reached threshold in the storage of fats, by inhibiting or cutting off fat supply to it, they won't have need to replicate further and this still boils down to inhibiting fat or cholesterol synthesis.
Even if their replication is stopped and cholesterol synthesis continues, they will continue to build up in other parts of the body and most especially the liver. Infact, it will be a worst case scenario.
So quenching the source, solves the problem rather than quenching the product storage.
A beautiful weekend to you too sir 🥰
OK now it is clear. I thought it was much simpler bu I didn't think adipocytes could have additional functions. Therefore, the quote below says it all:
Thanks for enlightening me with so many details, and have a nice week-end!