Potassium Citrate
pH
Between 7 and 9
Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases
https://pmc.ncbi.nlm.nih.gov/articles/PMC10861303/
Potassium, Magnesium, and Calcium: Their Role in Both the Cause and Treatment of Hypertension
https://pmc.ncbi.nlm.nih.gov/articles/PMC8109864/
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Gilbert Ling
Raymond Damadian
https://www.gilbertling.org/theories-and-publications.html
Nano-protoplasm: the Ultimate Unit of Life
Intercellular
Potassium / Sodium
Cardiac Glycoside
Nano Protoplasm
Water Structure
Hydrophilicity Hydrophobicity
Hormone
Progesterone
Red blood cell's cytoplasmic protoplasm, which comprises almost entirely of hemoglobin, water, K+ and ATP.
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Potassium
Rubidium
Selenium
Tellurium
NAC
Selenium
Potassium
Polyphenol
Terpine
Castor
https://en.m.wikipedia.org/wiki/Anti-structure
https://en.m.wikipedia.org/wiki/Potassium_selenide
https://en.m.wikipedia.org/wiki/Selenium
https://en.m.wikipedia.org/wiki/Tellurium
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Selenium
Tellurium
Selenoenzyme
Selenoprotein
Selenocysteine
Selenocystine
Selenomethionine
Selenium is a chemical element; it has the symbol Se and atomic number 34.
It has various physical appearances, including a brick-red powder, a vitreous black solid, and a grey metallic-looking form. It seldom occurs in this elemental state or as pure ore compounds in Earth's crust.
Selenium is found in metal sulfide ores, where it substitutes for sulfur. Commercially, selenium is produced as a byproduct in the refining of these ores.
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is Selenium doing something with Potassium & Sulfur?
Flipping Anion & Cation?
Anti-Structure
Potassium Sulfate
anti-structure, called the antifluorite structure, anions and cations are swapped.
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Selenium belongs to the category of redox nonmetals. Selenium is included in the same class with sulfur metalloids, which implies that selenium should be able to substitute for sulfur in biological complexes. As a congener of sulfur, selenium becomes part of a protein's structure as selenocysteine and selenomethionine, not as a selenium atom ligated directly to the protein as a prosthetic group. The former are the active cofactors in selenium enzymes.
The biological significance of Se is predominantly dependent on its incorporation into the selenocysteine (Sec) for synthesis of selenoproteins (SePs), such as thioredoxin reductase family enzymes and glutathione peroxidase family enzymes.
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Methane, arsenic, selenium and the origins of the DMSO reductase family
https://www.nature.com/articles/s41598-020-67892-9
N-Acetyl-l-cysteine Enhances the Effect of Selenium Nanoparticles on Cancer Cytotoxicity by Increasing the Production of Selenium-Induced Reactive Oxygen Species
https://pmc.ncbi.nlm.nih.gov/articles/PMC7254790/
https://www.sciencedirect.com/topics/medicine-and-dentistry/selenium-ion
Rubidium and potassium levels are altered in Alzheimer’s disease brain and blood but not in cerebrospinal fluid
https://pmc.ncbi.nlm.nih.gov/articles/PMC5109650/
The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease
https://www.sciencedirect.com/science/article/pii/S0925443915002811
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Epidermal Barrier
NHE1
Sodium-Proton Antiporter
Stratum Corneum
Corneodesmosome
Corneocyte
Lamellae
Filaggrin (FLG)
Ceramide
Serine Protease (SP)
Acidifying
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Sodium-Calcium Exchanger
Potassium-Dependent Sodium-Calcium Exchanger
Calcium-Activated Potassium Channel
Paroxysmal Depolarizing Shift
https://en.m.wikipedia.org/wiki/Sodium-calcium_exchanger
https://en.m.wikipedia.org/wiki/Potassium-dependent_sodium-calcium_exchanger
https://en.m.wikipedia.org/wiki/Paroxysmal_depolarizing_shift
https://en.m.wikipedia.org/wiki/Calcium-activated_potassium_channel
Histamine
Histidine
Histone
Histone Octamer
Creatinine
Histamine
Nitrogen
Niacin
https://pubchem.ncbi.nlm.nih.gov/compound/histidine
https://pubchem.ncbi.nlm.nih.gov/compound/histamine
https://en.m.wikipedia.org/wiki/Histone
https://en.m.wikipedia.org/wiki/Histone_octamer
The Pathological Cascade of DNS
Brain White Matter & Demyelinating Events: The hallmark pathological feature of DNS is extensive demyelination, where the protective myelin sheath surrounding nerve fibers in the brain's white matter is destroyed. This halting of nerve signaling prevents normal communication between different brain regions.
Basal Ganglia Injury: The basal ganglia (specifically the globus pallidus) are highly metabolically active and among the first structures damaged during severe systemic hypoxia. Ischemia and metabolic failure here contribute significantly to motor and cognitive deficits.
Hyperintense Lesions: On neuroimaging (T2-weighted MRI), this tissue damage and cellular edema appear as bright or "hyperintense" white matter lesions. These signals highlight areas of active inflammation, demyelination, and fluid buildup.
Neuroinflammation: The initial hypoxic injury triggers a severe secondary immune response. Microglia become activated, releasing inflammatory cytokines that perpetuate the breakdown of the blood-brain barrier and cause ongoing damage to oligodendrocytes (the cells responsible for producing myelin).
Psychiatric Psychosis: When the demyelination and neuroinflammation affect the frontal lobes, limbic system, and basal ganglia, the brain's complex neural networks are disrupted. This leads to the psychiatric manifestations of DNS, which can include sudden-onset psychosis, catatonia, severe paranoia, and disorganized behaviors.
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Dr. Joseph Mercola has promoted the controversial and unproven practice of "rectal carbon dioxide insufflation" (introducing carbon dioxide gas into the rectum) as a way to feed gut bacteria, improve mitochondrial energy production, and promote overall health.
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Hypercapnia
Hypercapnic
Encephalopathy