Branched-Chain Amino Acid
https://en.m.wikipedia.org/wiki/Branched-chain_amino_acid
CHONS
Amino Precursor
Nixtamalization
Neutral pH 7.40
Honey 70%
Castor 10%
Niacin 5%
MSM 5%
Citrus 5%
Minerals 5%
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Castor
DMSO
Betaine HCL
Glycerol
Glycine
Magnesium Chloride
Vitamin C
..
all the Nitrogen & Sulfur combinations seem to require MG2+ "Magnesium" to function correctly.
Thiamine
Taurine
Cysteine
Methionine
Methylene Blue
Fenbendazole
NAC
SAM-e
Glutathione
..
Molecular Motors
Cellular Rotation
F0 F1 Synthase
Proton Hydrogen
Magnesium Ion
NAD ATP DNA
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Sulfur Toxicity
Hyperhomocysteinemia
Cysteine
Phosphorus Toxicity
Choline
Trimethylaminuria
Nitrogen Toxicity
[Sulfur Toxicity]
Hyperhomocysteinemia
Methyl-Hydrogen-Folate
MTHFR
Methionine
Histamine
Homocysteine
Cysteine
Choline
Betaine
Methylamine
Trimethylamine
Trimethylaminuria
[Nitrogen Toxicity]
TMAO
TMAU
Acetaldehyde Dehydrogenase
Fomepizole (Nitrogen)
Disulfiram (Sulfur)
Acetyl-CoA
N-Acyl Amide Acetyl Amine Amino Acid
Aldehyde
Acetaldehyde
Histamine
Homocysteine
..
pH Alkaline
Detox
Bath Salts
Baking Soda
Epsom Salt
Sodium Bicarbonate Magnesium Sulfate
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Olive Oil (95%)
DMSO (4%)
Magnesium Chloride
Potassium Citrate
Citric Acid
Pine Terpinene
Vinegar
Honey
Gluconate
Dextran
Carbanion
Caramelization
Decarboxylation
..
Fenbendazole
Castor Oil
Pine Terpinene
NAC
Niacin
TMG
MSM/DMSO
Quercetin
Magnesium Chloride
..
Sodium Sulfate
Vs
Sodium Sulfide
https://en.m.wikipedia.org/wiki/Sodium_sulfate
https://en.m.wikipedia.org/wiki/Sodium_sulfide
https://en.m.wikipedia.org/wiki/Sodium_citrate
https://en.m.wikipedia.org/wiki/Chondroitin_sulfate
https://en.m.wikipedia.org/wiki/Dodecanol
https://en.m.wikipedia.org/wiki/Sodium_dodecyl_sulfate
https://en.m.wikipedia.org/wiki/Thrombocytopenia
https://en.m.wikipedia.org/wiki/Dextran_sulphate_sodium
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DSS
Dextran Sodium Sulfate
Colitis
Thrombocytopenia
Familial Alopecia
https://en.m.wikipedia.org/wiki/Thrombocytopenia
Coagulation Disorder
Low levels of platelets (thrombocytes) in the blood.
Bone marrow not making enough platelets, body destroying platelets, spleen holding too many platelets.
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Small Cell Lung Cancer Presenting as Severe Thrombocytopenia and Refractory Hypokalemia
https://pmc.ncbi.nlm.nih.gov/articles/PMC4052468/
platelet count had dropped with mild pain in extremities. Serum potassium was low.
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might have figured this DSS puzzle out, all of the negative side effects Sodium causes in the tests, Potassium reverses them.
so by doing the exact same thing but swapping buffered 7 pH Potassium Citrate instead of high Alkaline Sodium.
this may bind up HIV & also heal the body.
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DSS
Dextran Sodium Sulfate
Negatively Charged
Alkaline
Electrophilic Compound
Carboxylic Acid
Positively Charged
Acidic
https://pubchem.ncbi.nlm.nih.gov/compound/Dextran-Sulfate-Sodium
Dextran Sulfate Sodium Salt: A Game-Changer in Antiviral Research
https://www.losanglesnewswire.com/dextran-sulfate-sodium-salt-a-game-changer-in-antiviral-research
Unveiling Colitis: A Journey through the Dextran Sodium Sulfate-induced Model
https://pmc.ncbi.nlm.nih.gov/articles/PMC11063560/
The Alleviation of Dextran Sulfate Sodium (DSS)-Induced Colitis Correlate with the logP Values of Food-Derived Electrophilic Compounds
https://pmc.ncbi.nlm.nih.gov/articles/PMC9774124/
Lithospermic acid alleviates oxidative stress and inflammation in DSS-induced colitis through Nrf2
https://www.sciencedirect.com/science/article/abs/pii/S001429992500144X
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dextran sulphate owes its anti-HIV-1 activity mainly to inhibition of virus binding to its target cells. The anti-HIV-1 activity of dextran sulphate is highly dependent on its sulphate content.
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Gluconate
Gluconic Acid
C6H12O7
Dextran
Alpha Glucan
C18H32O16
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IHN
Inositol Hexanicotinate
MSM
Methylsulfonylmethane
NAC
N-Acetyl Cysteine
Vitamin C (Buffered)
Ascorbate Potassium
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The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases
https://pmc.ncbi.nlm.nih.gov/articles/PMC7554709/
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Redox Rhythms
Biorhythm Reset
Intercellular Homeostasis
Inositol (Sugar)
Hexanicotinate Nicotinate (Nitrogen)
MSM (Sulfur)
Potassium Citrate
found the combination that works best for all my random problems.
Inositol Hexanicotinate
Methylsulfonylmethane
its like a wave of cool ocean wind, amazing.
Grapefruit Juice
Potassium Citrate
to break up any Calcification or excess Sodium in mitochondria.
it appears to be the combination to unlock Coenzyme-A, that is disrupted by toxins & pesticides.
rain water has both Nitrogen & Sulfur drawn up from the ocean, and the right amout of Oxygen to make it perfect.
nobody knows about this and the connection to Coenzyme-A, and it looks identical to NAC N-Acetyl Cysteine, except NAC dosnt have the same calming effect.
once Coenzyme-A is unlocked, all the poisons fall out almost instantly.
Chelation Therapy seem to always drop the toxic load across the entire body, requiring lots of perfectly timed medication?
what ive noticed is one capsule each of MSM & IHN, both white powders, and urine comes out dark, totally chelated out toxins.
IHN releases Niacin for 12 hours, Methylated Niacin.
Inositol Nicotinate, Non-flush Niacin, Inositol is a Methyl Doner.
Niacin needs a Methyl Doner as a buffer, and Sulfate to metabolize toxic sludge, pesticides ect..
Methylated Niacin & MSM
Methyl Donor
Methylation
Osmolyte
Inositol
Betaine
i didnt ever make that connection, all of the years learning, it never occurred to me.
Methylated Niacin
Buffered Niacin
thats crazy, all this time fiddling with Betaine, and Inositol is basically a Osmolyte & Methyl.
and the only difference between this & Methylene Blue is the blue part is Chloride folding a Polyphenol into a specific spectrum.
the non-flush Inositol Niacin is totally under reported, almost no significant documented test results, it normally feels like nothing is happening at all, until the MSM is applied.
and it only takes a single capsule of each, for 12 hours of metabolic movements.
Niacin needs a Methyl Doner as a buffer, and Sulfate, to metabolize toxic sludge, pesticides ect..
Methylated Niacin
Buffered Niacin
Betaine and Inositol basically a Osmolyte & Methyl.
Niacin is required break down Formaldehyde.
Aldehyde
Acetaldehyde
Formaldehyde
Acetaldehyde Dehydrogenase
Niacin with MSM (Sulfate) helps make Coenzyme-A (CoA) for Glutathione & Redox.
add some good minerals to that breaks up kidney & liver sludge.
Potassium Citrate
Magnesium Citrate
Calcium Citrate
Sodium Bicarbonate
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Reversing Chronic Kidney Disease with Niacin and Sodium Bicarbonate
https://www.orthomolecular.org/resources/omns/v17n22.shtml
Niacin Was, Is, and Always will be Essential to Life and the Prevention of Cardiovascular Disease
https://www.orthomolecular.org/resources/omns/v20n03.shtml
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GPR109A
Niacin Receptor 1 (NIACR1)
Hydroxycarboxylic Acid Receptor 2
https://en.m.wikipedia.org/wiki/Hydroxycarboxylic_acid_receptor_2
Butyric Acid
https://en.m.wikipedia.org/wiki/Butyric_acid
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Nicotinic Acid Decarboxylation
https://chempedia.info/info/nicotinic_acid_decarboxylation/
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apparently stomach acids get weak as we get older, Hydrogen Chloride HCL needs to be higher to metabolize Magnesium into MG2+ & split water molecules into free Hydrogen, for the Proton Pumps to pumup out MG2+ at 400 cycles a second, that makes NAD & ATP for cellular energy.
all the medications that really get down & kill cancers & parasites use the Nitrogen Sulfur combo, and thats what breaks down carbohydrates into energy via Coenzyme-A.
problem is for that to even happen seems to requires Magnesium to do anything for NAD & ATP cellular metabolism.
so my take is Magnesium is step one, Nitrogen Sulfur is like step ten.
Magnesium blood tests are inaccurate, and is difficult to get into the cells with the correct ion state MG2+, so it needs a binder component like amino acids or Vitamin C.
then Magnesium flips Triglycerides & LGL into HDL (good Cholesterol), then converts into Hormones, Steroids & Myelin.
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Methylene Blue
Potential side effects include headache, diarrhea, and low potassium and magnesium levels.
Warning in patients with G6PD deficiency and those taking medications that affect serotonin levels.
Magnesium acts as a cofactor for tryptophan hydroxylase, an enzyme involved in serotonin synthesis. It also plays a role in serotonin receptor binding.
Magnesium is involved in regulating other important neurotransmitters like GABA (inhibitory) and glutamate (excitatory). It helps regulate their release and interacts with NMDA receptors.
Potassium, Magnesium, and Calcium is associated with a reduced risk of stroke.
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anything to do with Nitrogen & Sulfur requires extra Magnesium & Potassium.
oil based vitamins (ADEK) require Magnesium & Potassium to form good cholesterol like Myelin.
Molecular Motors, Cellular Rotation & Proton Pumps that form NAD ATP DNA, require Magnesium & Potassium Ions.
magnesium naturally fixes Potassium deficiency.
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Myelin Myelitis refers to inflammation of the spinal cord that damages the myelin sheath, a protective covering of nerve fibers.
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Magnesium L-Threonate
Magnesium L-threonate is a magnesium salt of L-threonic acid having the formula Mg(C4H7O5)2.
Threonic acid is a sugar acid derived from threose. The l-isomer is a metabolite of ascorbic acid (vitamin C).
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Magnesium regulates activity of the renal outer medullary potassium (ROMK) channel. Intracellular magnesium is inversely proportional to the open ROMK channel pore. Therefore low intracellular magnesium causes more ROMK channels to open, allowing more K+ efflux into the urine.
Magnesium's Role in Retinol Metabolism: Magnesium is required for the activation of enzymes involved in vitamin A metabolism. This suggests that adequate magnesium levels are necessary for optimal vitamin A function.
Magnesium deficiency can lead to an accumulation of nitrogen in the form of nitrates and amides, rather than their incorporation into proteins.
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Magnesium Taurinate
Taurinate = NAC
Threonate = Ascorbate
https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-taurinate
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Synergistic Protection of N-Acetylcysteine and Ascorbic Acid 2-Phosphate on Human Mesenchymal Stem cells Against Mitoptosis, Necroptosis and Apoptosis
https://www.nature.com/articles/srep09819
The Role of Oral Ascorbic Acid Administration in Combination With IV N-acetylcysteine in Delaying Inflammatory Cascade in Sepsis: A Case Report
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L-Ascorbic Acid 2-Phosphate Magnesium Salt Hydrate
Magnesium Ascorbyl Phosphate (MAP)
N-Acetylcysteine
https://www.vernoncoleman.com/main.htm
https://vedicinalsusa.com/products/vedicinals9-advanced
Baicalin, Quercetin, Luteolin, Rutin, Hesperidin, Curcumin, EGCG, Piperine, and Glycyrrhizin, as well as Vitamin C, D3, Zinc, and Selenium
Baicalin (Skullcap, Mint)
Quercetin (Oak, Caper)
Luteolin (Dandelion, Rosemary)
Rutin (Caper, Buckwheat)
Hesperidin (Citrus, Peppermint)
Curcumin (Turmeric Cinnamon)
EGCG (Catechin, Tea)
Piperine (Black Pepper)
Glycyrrhizin (Liquorice Root)
Vitamin C, D3, Zinc, and Selenium
composition of super glue 502-ethyl cyanoacrylate
https://en.m.wikipedia.org/wiki/Nitrile
https://en.m.wikipedia.org/wiki/Ethyl_cyanoacetate
Cycloaddition
Amino Acid
Pyrrole
Furan
Furfural
Hydroxymethylfurfural (HMF)
5-Hydroxymethylfurfural (5-HMF) is one of the most promising molecules with huge synthetic potential.
https://en.m.wikipedia.org/wiki/Nitrile
https://en.m.wikipedia.org/wiki/Nisin
https://en.m.wikipedia.org/wiki/Nitrone
https://en.m.wikipedia.org/wiki/Nitronate
https://en.m.wikipedia.org/wiki/N-Oxoammonium_salt
Magnesium Taurinate
Magnesium Threonate
Magnesium Glycinate
Taurinate
Threonate
https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-taurinate
Glyphosate is known to chelate or bind with magnesium ions and other divalent cations.
Chelation: Glyphosate acts as a chelating agent, meaning it forms stable complexes with metal ions, including magnesium (Mg²⁺).
Reduced Availability: When glyphosate binds to magnesium, it reduces the availability of these essential minerals to plants. This can impact plant growth and health because magnesium plays a crucial role in processes like photosynthesis.
Impact on Herbicide Effectiveness: Hard water, which contains high concentrations of magnesium and calcium ions, can interfere with the effectiveness of glyphosate-based herbicides.
The positively charged magnesium ions bind with the negatively charged glyphosate molecules, making the herbicide less readily absorbed by plants.
Magnesium can promote the formation and enhance the survival of chondrocytes, the specialized cells responsible for producing healthy cartilage.
Magnesium ions (Mg2+) play a beneficial role in cartilage health and repair. They promote chondrocyte viability, matrix synthesis, and the proliferation of bone marrow-derived stromal cells. Mg2+ can also enhance chondrogenesis by synovial mesenchymal stem cells.
Magnesium plays a crucial role in maintaining hair health, particularly by impacting keratin production and follicle strength. Magnesium is essential for protein synthesis, including keratin, the main protein in hair.
It also helps maintain healthy hair follicles by reducing calcium buildup on the scalp, which can clog follicles and hinder hair growth. Furthermore, magnesium aids in blood flow to the scalp, delivering vital nutrients to the hair follicles.
Magnesium ions are associated with tubulin and play a crucial role in microtubule assembly and dynamics.
Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch
https://www.nature.com/articles/s42003-023-05175-5
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SAM/SAH Riboswitch deactivation is likely responsible for the Homocysteine problems, where the metabolism gets locked up with a cascade of Inflammation.
Magnesium facilitates the release and function of GABA in the brain. It acts as a cofactor for enzymes involved in GABA synthesis, ensuring that our calming neurotransmitter is produced in adequate amounts.
Dechelation of green chlorophyll to yellow pheophytin Dechelation: In an acidic environment, chlorophyll's green color degrades into a brownish-yellow compound called pheophytin.Mechanism: This occurs as hydrogen ions ((H^{+})) from the acid replace the central magnesium ((Mg^{2+})) ion in the chlorophyll molecule. This change in the molecule's structure shifts the pigment, resulting in the olive-brown or yellowish color.Example: This is a common process in food science, where vegetables lose their vibrant green color during cooking or pickling due to the presence of acids. Lactic acid fermentation, which lowers the pH, also drives this chemical reaction. Fermentation by yeast Process: Yeast (e.g., Saccharomyces cerevisiae) can ferment plant material, consuming sugars and producing organic acids, carbon dioxide, and other compounds.Nutritional enhancement: As part of this process, yeast can increase the nutritional quality of food. This includes synthesizing B vitamins (especially B9 and B12 in fortified versions) and breaking down complex molecules into more bioavailable nutrients.Polyphenol synthesis: During fermentation, microorganisms can also secrete enzymes that alter the plant's existing polyphenols. This can release bound phenolic compounds, modify their structure, and produce new, smaller phenolic molecules that have enhanced bioactivity. Ascorbate metabolism Limited synthesis: While yeasts are known to produce various vitamins, the industrial production of ascorbic acid ((C_{6}H_{8}O_{6})) or vitamin C typically involves a two-step fermentation process by specific bacteria, not yeast alone.Degradation in plants: In plants, L-ascorbic acid and other phenolic compounds degrade during fermentation, particularly in anaerobic solid-state fermentation. Proposed integrated process and outcome Based on the described steps, here is how the integrated process would likely unfold and what the final product would be: Preparation: Green plant material containing chlorophyll is shredded and salted.Lactic acid fermentation: The natural sugars in the plant material are fermented by lactic acid bacteria. This produces organic acids, causing the pH to drop and initiating the dechelation of chlorophyll.Color change: The acidic environment causes the chlorophyll to lose its central magnesium ion and turn into yellowish-brown pheophytin.Yeast and nutrient enhancement: The addition of "nutrition enhanced yeast" would supplement the fermentation, producing B vitamins, including B12, and potentially improving the bioavailability of minerals like zinc and selenium.Antioxidant modification: The yeast's enzymatic activity would release bound polyphenols from the plant's cell walls, increasing the total antioxidant content and bioavailability.Flavor profile: The combination of lactic acid fermentation and yeast activity would result in a complex, tangy flavor profile characteristic of fermented vegetables and other yeast-fermented products. The end result would be a nutritionally dense, yellowish, and sour-tasting fermented food. The sour taste would come from the organic acids produced during fermentation, and the color change from green to yellow would be the result of acid-driven pheophytin formation. The nutritional value would be enhanced by the yeast, increasing its vitamin and mineral content.
Hydrogen Tablets
H2 Tablets
Contain the following ingredients:
Magnesium: The primary ingredient that reacts with water to produce molecular hydrogen gas.
Citric Acid or Tartaric Acid: An acidic component that helps the magnesium dissolve in water.
Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways
https://www.nature.com/articles/s41598-022-07710-6
Oxidative Phosphorylation
(OxPhos)
Electron Tansport Chain
(ETC)
Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein.
https://pmc.ncbi.nlm.nih.gov/articles/PMC1220878/
High-dose vitamin C blocks HOCl production by Myeloperoxidase: A potential therapeutic strategy
https://www.sciencedirect.com/science/article/pii/S0006291X25009283
Our observation of methionine oxidation by oxidized ascorbate suggests another potential pathway for the anticancer effects of high-dose vitamin C. Cancer cells are more sensitive to methionine restriction compared to normal cells. This phenomenon, known as methionine auxotrophy [56] —where cancer cells cannot grow without methionine while normal cells remain unaffected—may play a role in the anticancer effects of DHA.
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Mitochondrial–Stem Cell Connection: Providing Additional Explanations for Understanding Cancer
https://pmc.ncbi.nlm.nih.gov/articles/PMC11051897/
Targeting the Mitochondrial-Stem Cell Connection in Cancer Treatment: A Hybrid Orthomolecular Protocol
https://isom.ca/article/targeting-the-mitochondrial-stem-cell-connection-in-cancer-treatment-a-hybrid-orthomolecular-protocol/
PI3K/AKT/mTOR
PI3K-mTOR Decoupling
SIN3-HDAC Inhibition
α-ketoglutarate (a-KG)
Chromatin Remodeling
Transcriptional Derepression
Histone Deacetylase HDAC
Chloride Channel Activation
PI3K/mTOR INHIBITION MARKEDLY POTENTIATES HDAC INHIBITOR ACTIVITY IN NHL CELLS THROUGH BIM- and MCL-1-DEPENDENT MECHANISMS
https://pmc.ncbi.nlm.nih.gov/articles/PMC4166554/
https://www.airmidbiogenetics.com/gene-reprogramming-paper
Ascorbate also directly modulates the PI3K/AKT/mTOR signaling pathway
Vitamin C Supplementation in Healthy Individuals Leads to Shifts of Bacterial Populations in the Gut—A Pilot Study
https://pmc.ncbi.nlm.nih.gov/articles/PMC8389205/
Chemical Stability of Ascorbic Acid Integrated into Commercial Products: A Review on Bioactivity and Delivery Technology
https://pmc.ncbi.nlm.nih.gov/articles/PMC8773188/
Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin
https://www.sciencedirect.com/science/article/pii/S0022202X1532491X
Biological and cellular effects when a fatty acid/DMSO mixture is introduced into a biological system:
Changes in lipid metabolism:Decreases fat accumulation: Studies on liver cells have shown that DMSO treatment can decrease overall lipid accumulation and increase fatty acid oxidation.
Induces autophagy: In a dose-dependent manner, DMSO can activate autophagy, a cellular process that degrades lipids. This mechanism contributes to the reduction of lipid content in cells exposed to fatty acids.
B vitamins and lipid synthesis
Primarily B-family, serve as crucial cofactors for enzymes involved in the synthesis of lipids such as fatty acids, triglycerides, and cholesterol.
Association Between Folic Acid Prescription Fills and Suicide Attempts and Intentional Self-harm Among Privately Insured US Adults
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2796907
study of folic acid found a beneficial association in terms of lower rates of suicide attempts.
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hydrogen proton donor ch3 methyl ascorbate
vitamin c hydrogen proton donor demethylation makes ch3 methyl donor & K2.