been testing thr honey vinegar both raw & heated for long enough to find some side effects.
taken too much will drop the pH to acic, and as a result will chelate essential minerals (electrolytes).
the problem i was having was sea salt & electrolyte formulas dont include Calcium, and its ratio is like 10 to 1 of importance.
once Calcium Ca2+ gets whacked out of place, it knocks out everything else.
Minerals Ratio:
10 mg/dL (Calcium)
2 mg/dL (Magnesium)
140 mmol/L (Sodium)
5 mmol/L (Potassium)
Calcium requires Magnesium & Vitamin D to metabolize effectively.
so if honey vinegar ever gets you feeling bad, you know how to reverse it.
other then that, its possible honey/vinegar can bind any/all parasitic pathogens.
..
Cortisol, Estrogen, Steroids, Cholesterol, hydrogen peroxide..
all connected to Calcium & Magnesium.
plants are the best source of Calcium & Magnesium.
Mike Whey is also high, and bone broth lowest.
wood ash, is highest in Calcium, because the plants know its the most important mineral.
milk bones for dogs.
my dog was German Shepherd, at 13 years his hips went out.
my thoughts were to give him dog muscle supliments, with a giant pit bull on the can.
he was looking good for a few months, exercise made him stronger.
but at night he would moan with pain.
come to find out its not hip dysplasia, it the lower spine collapsing.
one the spine shuts down the back legs its game over.
Calcium is to flex muscle, Magnesium is to relax, ion pumps.
no other supliment can replace this core mechanism.
plant wood ash is mostly Calcium for a reason, its important.
looking at what Glyphosate does, it chelates both Calcium & Magnesium out.
Electrolyte Ratio:
10 mg/dL (Calcium)
2 mg/dL (Magnesium)
140 mmol/L (Sodium)
5 mmol/L (Potassium)
no electrolyte supliments have Calcium included, and its required times 10 to the others.
meaning to duplicate,
(like from plant biomass ash)
would require 10 times all other minerals, then Magnesium as 1, then something like Sea Salts as 0.9s.
this also means taking any other supliments are likely to disrupt or even chelate away this Calcium 10 to Magnesium 1 homeostasis.
this is likely the core cause of electrolyte imbalances.
..
looking closer at the chemistrybiology of Calcium.
apparently the most important function of Vitamin D & Omega-3 is to retain Calcium in the gut renal cycles.
thats what they literally both do, Calcium is that important.
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7-Dehydrocholesterol chemistry synthesis
Synthetic Route (Windaus Modification):
bromination
dehydrobromination
N-bromosuccinimide (NBS),
acetate, tetrabutylammonium bromide, pyridine, or
collidine.
..
Hydrogenation
Oleandrose Sugar
Deoxysugar
Aglycone (Genin)
Oleandrigenin
Macrolide
Cardenolide
Cardiotonic Steroids
Dideoxyhexose
Lipophilicity
Digitoxin Toxicity
Electrolyte Disturbances
Hypokalemia
Hypomagnesemia
Low Levels:
Magnesium
Potassium
..
Ivermectin
Molecular Formula
C48H74O14
Avermectins are a group of potent anthelmintic and insecticidal macrocyclic lactones produced by the bacterium Streptomyces avermitilis. They feature a 16-membered polyketide-derived lactone ring (aglycone) linked to a disaccharide comprising two units of the methylated deoxysugar L-oleandrose.
Components: Consists primarily of carbon, hydrogen, and oxygen.
Structure: It is a large, complex molecule often referred to as a "sugar acid" derivative due to its glycosidic linkage to a disaccharide (oleandrose sugars).
Oleandrose Sugars:
Oleandrose is a rare dideoxyhexose sugar (a carbohydrate with two hydroxyl groups replaced by hydrogen) and a key sugar moiety found in cardiac glycosides like oleandrin and antibiotics like oleandomycin. It is characterized by having a methylated hydroxyl group at the C3 position and is often found as L-oleandrose.
Key Aspects of Oleandrose:
Structure: It is a methylated 2,6-dideoxy-hexose. The IUPAC name for L-oleandrose is (3S,4S,5S)-4,5-dihydroxy-3-methoxyhexanal.
Source: It is found in the poisonous plant Nerium oleander (common oleander) and in certain antibiotic-producing bacteria, specifically Streptomyces species.
Function: In N. oleander, it is a sugar component of oleandrin, a toxic cardiac glycoside with potent cytotoxicity. It is also part of the structure of avermectins (insecticides/anti-parasitics).
Oleander Note: While the prompt mentions "oleander," the sugar involved in avermectin is specifically L-oleandrose, a deoxysugar. Note that Oleandrin is a cardiac glycoside found in the Oleander plant (Nerium oleander), which is distinct from the microbial sugar L-oleandrose found in avermectins, although they share the same sugar component name.
Digitoxin and oleandrin are both cardiac glycosides that share a common mechanism of toxicity, which is heavily influenced by calcium levels. Both substances inhibit the sodium-potassium (Na+/K+) ATPase pump, leading to a cascade that ultimately increases intracellular calcium.
Mechanistic Link: The Role of Calcium
Intracellular Increase: By inhibiting the Na+/K+ ATPase pump, these toxins cause sodium to build up inside heart cells. This reverses or slows the sodium-calcium exchanger, leading to an accumulation of intracellular calcium.