It would take me a while to delve into everything here in detail, but the short answer is that Decred was built with ASICs in mind and their development is a favorable outcome. For example, a major consideration in the choice of the algorithm it uses was that fact that it can be efficiently implemented in hardware. The header was also designed with ASICs in mind such that the midstates can be calculated once and reused and it provides a space for extra nonces in order to ensure they don't have to spend time recalculating merkle roots every 232 iterations.
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