Hahaha well. This is gonna sound curious to you. But if I didn't have to be so extreme to choose to lose all three simultaneously and only choose two, the last sense that I would choose to lose is that of touch.
I think most people still do not realize its superlative importance in their life and how the sense of touch overlaps all the others in intensity and in relation to feeling truly alive. :)
Touch is one that some could get away without, I'm not sure if I could though.