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RE: Intercellular Homeostasis

in #intercellular14 days ago (edited)

Vitamin C Modes of Action in Calcium-Involved Signaling in the Brain

https://www.mdpi.com/2076-3921/12/2/231

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Unveiling the Therapeutic Potential of Folate-Dependent One-Carbon Metabolism in Cancer and Neurodegeneration

https://www.mdpi.com/1422-0067/25/17/9339

Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts

https://pmc.ncbi.nlm.nih.gov/articles/PMC7139526/

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Hydroxytyrosol

https://en.m.wikipedia.org/wiki/Hydroxytyrosol

Hyperammonemia

https://en.m.wikipedia.org/wiki/Hyperammonemia

Glutamate–glutamine cycle

https://en.m.wikipedia.org/wiki/Glutamate%E2%80%93glutamine_cycle

Tryptamine

https://en.m.wikipedia.org/wiki/Tryptamine

Folinic acid
Leucovorin

https://en.m.wikipedia.org/wiki/Folinic_acid

Levomefolic acid
Methylfolate

https://en.m.wikipedia.org/wiki/Levomefolic_acid

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Ascorbate (vitamin C) can regenerate oxidized polyphenols, thereby restoring their antioxidant properties. This is a synergistic process that enhances the overall antioxidant capacity of a system, such as a food product or the human body

The regeneration process is based on the superior reducing power of ascorbate, which allows it to donate electrons to other antioxidant compounds.

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ch3 methyl regeneration vitamin c ascorbate methionine folate (5-MTHF)

vitamin C treatment in cells significantly increased the production of 5-MTHF, which in turn increased methionine levels. This suggests that vitamin C can "activate" the folate-mediated one-carbon cycle.

vitamin C treatment in cells significantly increased the production of 5-MTHF, which in turn increased methionine levels. This suggests that vitamin C can "activate" the folate-mediated one-carbon cycle.

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Tetrahexyldecyl Ascorbate
THD
Nikkol VC-IP

Tetrahexyldecyl Ascorbate (THD) is a stable, oil-soluble form of Vitamin C, also known by the trade name Nikkol VC-IP, that penetrates the skin and is converted into active Vitamin C (ascorbic acid) to provide antioxidant benefits.

Tetrahexyldecyl ascorbate (THD), also known by the trade name Nikkol VC-IP, is synthesized by reacting ascorbic acid with 2-hexyldecanoic acid.

The name "isopalmitic acid" highlights that it is an isomer of palmitic acid, but with a branched, rather than linear, carbon chain.

It is typically described as a colorless to yellowish liquid, unlike linear palmitic acid, which is solid at room temperature.

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Ascorbyl Palmitate

Ascorbyl palmitate is synthesized primarily through the enzymatic esterification of ascorbic acid and palmitic acid.

Solvent:

An organic solvent is needed to dissolve the reactants, such as 2-methyl-2-butanol or dimethyl sulfoxide (DMSO).

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some new ideas

Ascorbyl Palmitate
Tetrahexyldecyl Ascorbate

synthetic Vitamin C & Oil compounds, the standard synthesis is a chemistry project.

the Castor & DMSO combination was not a good outcome, its too powerful in strange ways.

i mixed Ascorbic acid & Magnesium Chloride & Sea Salt, to see if it would become a better outcome.

ultimately it separated into 3 parts, a solid bottom of dark, a clear bottom sludge, and a clear top layer.

i have already had enough trouble with it in full strength, so mixed a little it into another powerful tincture.

Olive Oil, Olive Leaf, Rosemary & Oregano Extract.

previously the alcohol & oils from the tinctures never mixed & would sit on the skin for a long time.

now it almost evaporates into the skin immediately.

had to pour out the bottom sludge part, because it obviously will not mix, but the top liquid tastes like Vitamin C.

so hopefully no problems with this one, put on my toes for ongoing itchy problems, is always my first test.

for some reason that never seems to go away.

C regenerates Vitamin E, Glutathione, Folate, Polyphenols, and a bunch or other things i cant remember.

still having great results with B, C & Magnesium.

come to find out deep fried foods trans saturated oils, they directly strip away vitamin C into deficiency, its C that metabolizes the bad fat into good.